Blast Induced Neurotrauma

Soldier firing ordinance

Soldiers in combat settings are at high risk of exposure to blast-induced head injuries, both during operational training exercises and in the field. Blast Induced Neurotrauma (BINT) researchers investigate the mechanism of closed-head injury and the cumulative effects of repeated blast exposure and its relationship to neurodegenerative phenomena.

Using laboratory experiments, mathematical modeling techniques, and data captured in the field, BINT scientists work to develop standardized models of blast injury to improve coordination of research across diverse laboratories, produce high-fidelity simulations of head injury, study whether cellular- and organ-level processes in head trauma are a unique form of injury, and innovate new forms of personal protective equipment, such as improved helmet designs. Cumulatively, these efforts produce safer operating conditions for Soldiers.

Research Areas

Soldier with expolosives
Blast Exposure

BINT scientists work directly with Soldiers in training environments to measure blast exposure, as well as biomarkers and other physiological indicators, using these data to investigate how repeated blast exposure impacts homeostasis and therefore Soldier readiness.

blast simulator
Blast Simulation

Mathematical models that accurately simulate blast in the laboratory allow BINT researchers to identify neurobiological underpinnings of blast injury and establish effective countermeasures.