Military HIV Research Program

Scientist in MHRP lab

The U.S. Military HIV Research Program (MHRP) is at the forefront of the battle to protect U.S. troops from HIV and reduce its global impact. Since its inception in 1986, MHRP has emerged as a world leader in HIV diagnostics, threat assessment and epidemiology, and vaccine and functional cure research. With the persistent and destabilizing social, economic, and political impact of HIV/AIDS, high infection rates in many of the regions where military personnel are deployed, rising life-long treatment costs, and a sustained rate of new HIV infections in U.S. Service Members, MHRP’s HIV research and care mandates remain highly critical to military and civilian populations.

With an international network of research sites throughout Africa, Thailand, and Germany, the MHRP has achieved success through a combination of strong science, careful development of research sites, and partnerships with key research institutions in the U.S. and host countries. MHRP implements the President's Emergency Plan for AIDS Relief (PEPFAR) prevention and treatment initiatives, building strong and trusting relationships within the communities where research is conducted. For more information visit MHRP's website.

Research Areas

samples on instrument to be tested
HIV Diagnostics

MHRP oversees HIV testing for the Army, Army Reserve, and Army National Guard in addition to serving as the DOD's HIV reference laboratory. MHRP also serves as a hub for clinical trial specimens collected during U.S. military research, including from the Infectious Disease Clinical Research Program, MHRP, and WRAIR.

Doctor with syringe
Developing an HIV Vaccine

MHRP is dedicated to developing a safe and globally effective HIV vaccine to protect Soldiers wherever they may be deployed. MHRP led RV144, or the “Thai Study,” the first clinical trial to show a vaccine regimen was safe and modestly effective in preventing HIV infection. 

Woman in a lab
HIV Cure Research

MHRP's acute HIV infection cohorts provide insight into crucial stages of early HIV infection. By focusing on the earliest stages of infection, scientists hope to inform investigations into long-term HIV remission.

African children
PEPFAR

The President's Emergency Plan for AIDS Relief (PEPFAR) is the U.S. government initiative to prevent HIV. MHRP implements PEPFAR prevention and treatment initiatives in the African communities where research is conducted, providing an ethical, non-coercive environment to conduct clinical research.