Recruiting Studies

WRAIR #2847- Phase 1 COVID Vaccine Trial (EID030)

We are doing this research to test an experimental vaccine to prevent SARS-CoV-2, the virus that causes COVID-19 disease. A safe and effective vaccine is needed to prevent the COVID-19 disease, so we need to learn if the vaccine is safe and if it produces an appropriate immune response. The experimental vaccine cannot cause you to become infected with COVID-19.

To learn more about the Phase 1 vaccine trial or to enroll, contact the WRAIR Clinical Trials Center at 866-428-2788 or through email.

Duration:
18 months
Max Compensation:
$2475
Requirements
  • ✔ MUST
    be a healthy adult male or non-pregnant, non-breastfeeding female
  • ✔ MUST
    be between the ages of 18 & 55
  • ✔ MUST
    be willing and able to read, sign, and date the informed consent document before study-related procedures are performed
  • ✔ MUST
    be willing and able to participate in all planned study visits for the duration of the study
  • ✔ MUST
    have a body mass index (BMI) ≥18.1 and <35.0 kg/m2
  • ✔ MUST
    have no previously documented COVID-19 disease
  • ✔ MUST
    have acceptable screening laboratory results
  • ✔ MUST
    have a negative pregnancy test at screening and continue to use an acceptable method of birth control during the study
  • ✔ MUST
    be in good health based on the investigator’s clinical judgment when considering findings from past medical history, medication use, vital signs, and physical examination
  • ✘ CANNOT
    have plans to become pregnant or currently be pregnant or breastfeeding
  • ✘ CANNOT
    have donated a unit of blood within 8 weeks before day 1 or plan to donate blood during the course of the study
  • ✘ CANNOT
    have had a major surgery (per self-report) in the month prior to screening or plans to have major surgery during the study
  • ✘ CANNOT
    have any past or current infections with HIV, hepatitis C, or hepatitis B
  • ✘ CANNOT
    be unwilling to have their samples collected and stored for future research and genetic testing
  • ✘ CANNOT
    be healthcare workers including dental providers engaged in direct patient care
  • ✘ CANNOT
    have tattoos, scars, or other marks that would, in the opinion of the investigator, interfere with assessment of the vaccination site
  • ✘ CANNOT
    have known allergies or a history of anaphylaxis, or other serious reaction to a vaccine, vaccine component, or latex
  • ✘ CANNOT
    be currently participating in another clinical research study
  • ✘ CANNOT
    have a history of cancer
  • ✘ CANNOT
    have a history of autoimmune disease
  • ✘ CANNOT
    have diabetes mellitus (type I or II) and/or thyroid disease
  • ✘ CANNOT
    have any current or past history of substance abuse (alcohol or drug abuse, this includes current smokers: defined as an Adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes cigarettes)
  • ✘ CANNOT
    have a history of organ and/or stem cell transplantation
  • ✘ CANNOT
    have any serious medical illness or condition involving the heart, liver, lungs, or kidneys
  • ✘ CANNOT
    have history of other chronic disease or condition including: asthma, autoimmune disease, sickle cell anemia, chronic hepatitis or cirrhosis, and chronic cardiac disease including high blood pressure (hypertension)
  • ✘ CANNOT
    have major psychiatric illness during the last 12 months
  • ✘ CANNOT
    have any other physical or psychologic condition or laboratory abnormality that the study doctor thinks may increase your risk of having side effects or compromise the results of the study
  • ✘ CANNOT
    have received experimental treatment medicine three months before first study injection day or plan to receive experimental treatment medicine during the course of the study
  • ✘ CANNOT
    receive an experimental COVID-19 vaccine outside of this study or a COVID-19 vaccine that has been given Emergency Use Authorization from the FDA. You will be asked if you have received any of these vaccines at each study visit
  • ✘ CANNOT
    receive live attenuated vaccine from 30 days before Day 1 until 30 days after the last study injection
  • ✘ CANNOT
    receive killed or inactivated vaccine from 14 days before Day 1 until 30 days after the last study vaccination