Press Releases

U.S. Army Advances Lead COVID-19 Vaccine Candidate

A U.S. Army laboratory, the Walter Reed Army Institute of Research, a subordinate command of the Army Futures Command’s Medical Research and Development Command, announced the selection of a lead COVID-19 vaccine candidate a two backup vaccine candidates that will advance to the next stage of research. The candidates were narrowed down from more than two dozen prototypes in order to determine the candidates that elicited the most promising antibody response in preclinical studies.

Understanding the Initial Immune Response after Dengue Virus Infection

A study led by scientists at the Walter Reed Army Institute of Research sheds new light on the body’s initial response to dengue virus (DENV) infection, describing the molecular diversity and specificity of the antibody response.  These results, published in EBioMedicine, a journal published by The Lancet, identify a heretofore unappreciated role for DENV-reactive IgA antibodies. 

Army-developed Zika Vaccine Induces Potent Zika and Dengue Cross-neutralizing Antibodies

A new study led by scientists at the Walter Reed Army Institute of Research has shown for the first time that a single dose of an experimental Zika vaccine in a dengue-experienced individual can boost pre-existing flavivirus immunity and elicit protective cross-neutralizing antibody responses against both Zika and dengue viruses. Findings were published today in Nature Medicine.

Malarial Mosquitos Migrate Long Distances on High Level Wind Currents

Anopheles malaria vectors have been collected up to 290 meters up in the atmosphere, proving for the first time that they are able to undertake long-distance migrations. These findings argue that previously blood-fed, and therefore potentially infected, mosquitos travel significant distances, and that air-borne migration may be responsible for the introduction (or reintroduction) of malaria or other infectious diseases to the region – as is now thought to be the case during previous outbreaks in Israel and Egypt. These findings have significant impacts for control and elimination efforts for vector-borne disease; mosquito control efforts and vector hazard models will have to take long-distance migration into account.