SILVER SPRING, Md. – A new study led by scientists at the Walter Reed Army Institute of Research has shown for the first time that a single dose of an experimental Zika vaccine in a dengue-experienced individual can boost pre-existing flavivirus immunity and elicit protective cross-neutralizing antibody responses against both Zika and dengue viruses. Findings were published today in Nature Medicine.
Scientists from the Walter Reed Army Institute of Research have demonstrated that a novel, second-generation malaria vaccine candidate based on the tobacco mosaic virus may offer protection against Plasmodium falciparum malaria in the upcoming issue of the journal Proceedings of the National Academy of Sciences.
Scientists from the Walter Reed Army Institute of Research joined a network of African scientists, the Plasmodium Diversity Network Africa, and Wellcome Trust Sanger Institute to publish a groundbreaking study about the genetic diversity of the world’s most dangerous and prevalent species of malaria, Plasmodium falciparum across sub-Saharan Africa.
A team led by the Walter Reed Army Institute of Research has gained new insights into the mechanism of vaccine-induced T cell immunity utilizing single-cell RNA sequencing and metabolic profiling techniques. Though numerous vaccines induce and amplify T cells, a critical part of the body’s adaptive immune system, there is still an information gap regarding what determines the magnitude, diversity and persistence of that response.